Polycystic Ovarian Syndrome occurs when fluid-filled sacs are found on the surface of the ovaries (polycystic ovaries). Around 5% of women in the UK are believed to have Polycystic Ovarian Syndrome.
The causes of Polycystic Ovarian Syndrome are unknown, although it is believed to be genetic. The hormonal balance which regulates the activity of the body’s organs plays an important role. Luteinising hormone (LH) is produced by the pituitary gland and testosterone, produced in the ovaries are often found in higher levels than normal. These inbalances are what cause the irregular menstrual cycle, the hirsutism and other symptoms.
The body’s response to insulin also plays a key role. Despite increased production of insulin, the amount of sugar in the blood remains high. Insulin resistance can lead to increased testosterone levels, which, in turn tends to promote obesity.
Most women with polycystic ovarian syndrome start to notice problems in their late teens or twenties. Symptoms can include the following
If the typical symptoms of PCOS have been identified, an ultrasound may be the next step. With sufferers of PCOS, the ovaries appear enlarged or "polycystic", usually with 10 or more cysts, 6-8 mm in diameter, on the surface of the ovary. Affected ovaries are around three times larger than usual. Sometimes only one ovary may be affected.
If cysts are present at the ultrasound scan and there are also the typical physical symptoms, there may be no need to do blood tests. However, raised levels of a luteinising hormone and testosterone will confirm the diagnosis.
Various hormone-related imbalances can be used to diagnose Polycystic Ovarian Syndrome and in some countries, such as the US, it is hormone levels and symptoms, rather than the presence of cysts that are key to confirming a diagnosis.